Host modulators: a paradigm shift in the treatment of periodontitis

– Guidelines for the periodontitis treatment: 4 main stages

– Additional therapy for subgingival instrumental treatment

– Modulator of the host organism: biological justification for use

– Theory of polymicrobial synergy and dysbiosis

– The role of inflammation in the pathogenesis of periodontitis: paradigm shift

– Evidence base for the use of the host body modulator:

- Sub-antimicrobial dose of doxycycline (SSD)

- Local use of statins

- Local application of bisphosphonates

- Local use of metformin

- Non-steroid anti-inflammatory drugs

- Omega-3 polyunsaturated fatty acids

- Use of probiotics

- Micronutrients and vitamins.

Recommended for: Implantologist, Periodontist, General dentists.